Information for Healthcare Providers

Download the guidelines for referring clinicians

Includes overview of treatment indications and patient suitability, method of action, efficacy, safety and patient reported outcomes, and relevant clinical references.

Download Clinical Guide

Please provide your details to receive our clinical guideline booklet

Rhenium-SCT®

How does it work?

Rhenium-SCT® utilises the beta particles emitted during the decay of the radioactive isotope, rhenium-188, to destroy cancer cells.2 Beta particles induce direct local cytotoxic effects, such as apoptosis, as well as an immune reaction.2

> 0 %

complete response

> 0 %

excellent or good cosmesis

Patients to consider for 
Rhenium-SCT®

  • Rhenium-SCT® has successfully treated:2,3,5

    • BCC and SCC lesions, including:
      • Superficial and nodular tumours
      • Infiltrative and ulcerated tumours, and
      • Recurrent tumours.

    Difficult-to-treat areas treatable with Rhenium-SCT® include: 2,3,5,6

    • Face (including nose, ear and lip)
    • Digits
    • Genitals
    • Locations where wound closure might be more challenging.2

Rhenium-SCT® has successfully treated:2,3,5

  • BCC and SCC lesions, including:
    • Superficial and nodular tumours
    • Infiltrative and ulcerated tumours, and
    • Recurrent tumours.

Difficult-to-treat areas treatable with Rhenium-SCT® include: 2,3,5,6

  • Face (including nose, ear and lip)
  • Digits
  • Genitals
  • Locations where wound closure might be more challenging.2
  • Malignant melanoma
  • Skin tumours affecting nerves or bony structures
  • Lesions of the upper eyelid
  • Lesions which anatomical position does not allow a proper application of the Rhenium-SCT resin/paste
  • Confirmed pregnancy or impossibility to rule out a pregnancy
  • Illnesses which require medication that significantly suppresses wound healing or the immune system
  • Patients under 18 years
  • Existing major circulatory disorders in the region to be treated

Treatment process

Rhenium-SCT® (Skin Cancer Therapy) is a form of nuclear medicine that utilises the Beta emitter radioisotope rhenium-188 for the treatment non-melanoma skin cancer.

Picture 2

1

Diagnosis and Depth Determination

Following visual identification of suspicious lesions, the clinician will perform a punch or excisional biopsy to confirm diagnosis and maximum depth

RHEN-Demo-Step-1-scaled-compressed

2

Lesion Demarcation & Referral

If the histopathology report indicates a BCC or SCC < 3mm deep, the patient may be suitable for Rhenium-SCT if they are not good surgical candidates. If referring for a Rhenium-SCT consultation, lesion demarcation, preferably using dermoscopy, is helpful for treatment planning. The referring clinician should provide good quality clinical photography with lesion demarcation and pathology reports as part of the referral process.

RHEN-Demo-Step-3-scaled-compressed

3

Treatment

On treatment day, the clinician will demarcate the lesion based on the report and photography provided by the referring skin specialist, to ensure precise application of the resin. The rhenium resin is applied onto adhesive film affixed to the lesion, thereby avoiding direct contamination of the skin with the radioactive resin. Precise treatment time is calculated using the activity applied and the biopsy-determined lesion depth – the range is usually 30-180 minutes. The treatment is painless, and the patient sits comfortably until the treatment time elapses.

Picture 1

4

Aftercare & Followup

Once the resin is removed, the patient can immediately return to regular activities. They will not be radioactive. The treating clinician and nurse will provide them with aftercare advice, however, there is no complex procedures apart from keep the area clean. Patients will be informed of expected treatment reactions and timings. The area will become inflamed with crusting over the following weeks, which is a normal part of the radiodermatitis skin reaction. A follow-up visit will be planned with the treating clinic. The patient may also return to the referring clinician as part of their ongoing skin cancer surveillance and care. Further information is available on request for referring clinicians.

Rhenium-SCT® Application Suite

Engineered to ensure safety, convenience and quality control.

 

Healthcare Provider Enquiries

Healthcare providers can use this form to contact us for additional information or support.

 

Patient or Carer?

For general enquiries, please use the patient enquiry form and your request will be forwarded to a treatment centre for follow up.

    OncoBeta Australia
  • Patients
  • Healthcare Providers
  • Rhenium-SCT®
  • Find a Treatment Centre
  • More